Zox 100 mg/5 ml (30 ml) Powder for Suspension

Name: Zox 100 mg/5 ml (30 ml) Powder for Suspension
Brand: Square Pharmaceuticals PLC
SKU: PMX2345
Price: 40.00 BDT
Availability: InStock

Generic: Nitazoxanide

৳৪০/ PCS

১

সারা বাংলাদেশে ৩-৫ দিনের মধ্যে ডেলিভারি

ভুল বা ক্ষতিগ্রস্ত পণ্যে ২৪ ঘণ্টার মধ্যে সহজ রিটার্ন

১০০% আসল পণ্য, মান যাচাইকৃত ও নিরাপদ প্যাকেজিং

পণ্যের বিবরণ

Indications

Zox is indicated for the treatment of diarrhea caused by Cryptosporidium parvum, Giardia lamblia and Entamoeba histolytica.

Pharmacology

Nitazoxanide is a synthetic antiprotozoal agent for oral administration. The antiprotozoal activity of Nitazoxanide is believed to be interference with the Pyruvate Ferredoxin Oxido Reductase (PFOR) enzyme-dependant electron transfer reaction. This reaction is essential for anaerobic energy metabolism of the protozoa. Nitazoxanide and its metabolites, tizoxanid are active in vitro in inhibiting the growth of sporozoites and oocyst of Cryptosporidium parvum and trophozoites of Giardia lamblia.

Dosage & Administration

Age 1-3 years: 1 tea-spoonfull or 5 ml suspension every 12 hours for 3 days. Age 4-11 years: 2 tea-spoonfulls or 10 ml suspension every 12 hours for 3 days.Age 12 years or above: 5 tea-spoonfulls (25 ml) suspension or 1 tablet every 12 hours for 3 days. It is recommended to be administered with food.

Interaction

It is highly bound to plasma protein. Therefore, caution should be exercised when administering Zox concurrently with other highly plasma protein-bound drugs with narrow therapeutic index.

Contraindications

It is contraindicated in patients with known hypersensitivity to Nitazoxanide or any components of the preparation.

Side Effects

The most frequent side effects, reported by Zox are abdominal pain, vomiting and headache. These side effects are typically mild and transient in nature. Very rare side effects include- nausea, anorexia, flatulence, increased appetite, enlarged salivary glands, increased creatinine & SGPT level, pruritus, rhinitis, sweating, dizziness, discolored urine etc.

Pregnancy & Lactation

US FDA pregnancy category of Nitazoxanide is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Nitazoxanide have been shown to be excreted in human milk. So, caution should be exercised when Nitazoxanide is administered during lactation.